Publications

Original Kubios publications and white papers

The following publications describe certain functionalities of Kubios HRV software products or provide validation results for our HRV pre-processing and analysis algorithms. If you are using Kubios HRV software products in scientific research, we hope that you will cite these publications appropriately when you publish your research findings.

Publication Publication type & year Relevance/Context
Tarvainen MP, Lipponen JA, Niskanen J-P, and Ranta-aho PO. Kubios HRV Software User’s Guide. User’s Guide
2021
Documentation of Kubios HRV software features and functionalities (Kubios HRV Standard and Premium).
Lipponen JA and Tarvainen MP. Accuracy of Kubios HRV software respiratory rate estimation algorithms. Kubios white paper, June 2021. White paper
2021
Validation of the respiratory rate estimation algorithms (used in Kubios HRV Premium software).
Lipponen JA and Tarvainen MP. A robust algorithm for heart rate variability time series artefact correction using novel beat classification. J Med Eng & Technol, 43(3):173-181, 2019. Journal article
2019
Validation of the automatic beat correction algorithm (used in Kubios HRV Premium and Kubios Cloud analysis services).
Tarvainen MP, Laitinen TP, Lipponen JA, Cornforth DJ, and Jelinek HF. Cardiac autonomic dysfunction in type 2 diabetes – effect of hyperglycemia and disease duration. Front Endocrinol, 5(Article 130):1-9, 2014. Journal article
2014
Validation of Kubios HRV analysis methods in detecting cardiac autonomic dysfunction related to type 2 diabetes.
Tarvainen MP, Niskanen J-P, Lipponen JA, Ranta-aho PO, and Karjalainen PA. Kubios HRV – Heart rate variability analysis software. Comp Meth Programs Biomed, 113(1):210-220, 2014. Journal article
2014
Latest scientific reference for Kubios HRV software (version 2.1).
Tarvainen MP, Georgiadis SD, Laitio T, Lipponen JA, Karjalainen PA, Kaskinoro K, and Scheinin H. Heart rate variability dynamics during low-dose propofol and dexmedetomidine anesthesia. Annals Biomed Eng, 40(8):1802-1813, 2012. Journal article
2012
Validation of the Kalman smoother based time-varying spectrum estimation method (available in Kubios HRV Premium) in anesthesia monitoring.
Tarvainen MP, Georgiadis SD, Ranta-aho PO, and Karjalainen PA. Time-varying analysis of heart rate variability signals with Kalman smoother algorithm. Physiol Meas, 27(3):225-239, 2006. Journal article
2006
Description of the Kalman smoother based time-varying spectrum estimation method (available in Kubios HRV Premium).
Niskanen J-P, Tarvainen MP, Ranta-aho PO, and Karjalainen PA. Software for advanced HRV analysis. Comp Meth Programs Biomed, 76(1):73-81, 2004. Journal article
2004
Original scientific reference for Kubios HRV software (version 1.1).
Tarvainen MP, Ranta-aho PO, and Karjalainen PA. An advanced detrending method with application to HRV analysis. IEEE Trans Biomed Eng, 49(2):172-175, 2002. Journal article
2002
Scientific reference for the smoothness priors detrending method (used in Kubios HRV software products).